Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.63 |
| ▸ | FAAH | O00519 | 1/20 | 0.61 |
| ▸ | MGLL | Q99685 | 1/20 | 0.61 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.57 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TDO2 | P48775 | 1/20 | 0.48 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725608 | 0.86 | NR1H3 (0.67) | FAAHMGLLNR1H3SCN2AMEN1 | |
| SCHEMBL1735146 | 0.83 | ESR1 (0.57) | PGRFAAHMGLLNR1H3SCN2A | |
| SCHEMBL14268808 | 0.81 | NPC1 (0.57) | PGRFAAHMGLLNR1H3POLB | |
| SCHEMBL15438319 | 0.80 | FAAH (0.56) | PGRFAAHMGLLNR1H3POLB | |
| SCHEMBL5013757 | 0.80 | HSD17B10 (0.64) | POLBCTDSP1MEN1KMT2AALDH1A1 | |
| SCHEMBL3477804 | 0.79 | ESR1 (0.64) | NR1H3SCN2APOLBCTDSP1MEN1 | |
| SCHEMBL2553055 | 0.78 | KDM4E (0.68) | PGRMGLLNR1H3SCN2AMEN1 | |
| SCHEMBL8474317 | 0.78 | NR1H3 (0.64) | FAAHMGLLNR1H3SCN2AMEN1 | |
| SCHEMBL448847 | 0.78 | KMT2A (0.64) | PGRMGLLNR1H3SCN2APOLB | |
| SCHEMBL18229776 | 0.78 | FAAH (0.53) | PGRFAAHMGLLPOLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746342-B | Preparation method of hydroxy lactam | 南方科技大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-110734384-B | Preparation method of hydroxyamide | 南方科技大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-110746342-A | Preparation method of hydroxy lactam | 南方科技大学 | 2020-02-04 | — | — | CN | disclosed |
| CN-110734384-A | Preparation method of hydroxyamides | 南方科技大学 | 2020-01-31 | — | — | CN | disclosed |
| EP-0706521-A1 | NOVEL IMIDES | CELGENE CORPORATION (US) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001348-A2 | IMIDES AS INHIBITORS OF TNP ALPHA | CELGENE CORPORATION (US) | 1995-01-12 | — | — | WO | disclosed |