Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isophthalic Acid SCHEMBL4651781 | 0.89 | CA12 (0.56) | L3MBTL1TDP1CA12CA1CA2 | |
| Isophthalic Acid SCHEMBL28864205 | 0.87 | GPR84 (0.54) | LMNAHDAC1HDAC8HDAC3HDAC4 | |
| Isophthalic Acid SCHEMBL3673276 | 0.87 | CA12 (0.54) | L3MBTL1TDP1CA12CA1CA2 | |
| Azelaic Acid SCHEMBL11389879 | 0.86 | GPR84 (0.57) | L3MBTL1TDP1LMNAMAPTHDAC1 | |
| Isophthalic Acid SCHEMBL29100400 | 0.86 | GPR84 (0.57) | L3MBTL1TDP1LMNAMAPTHDAC1 | |
| Isophthalic Acid SCHEMBL2380785 | 0.86 | GPR84 (0.57) | L3MBTL1TDP1LMNAMAPTHDAC1 | |
| Terephthalic Acid SCHEMBL5631843 | 0.85 | TSHR (0.52) | CA12CA1CA2CA6CA9 | |
| Terephthalic Acid SCHEMBL6892927 | 0.84 | GPR84 (0.50) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| Terephthalic Acid SCHEMBL6898217 | 0.83 | TSHR (0.50) | CA12CA1CA2CA6CA9 | |
| SCHEMBL2719666 | 0.83 | L3MBTL1 (0.56) | L3MBTL1TDP1LMNAMAPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648368-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1997-07-15 | — | — | US | disclosed |
| EP-0673247-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS. | MERCK & CO INC (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0673247-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994012181-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-09 | — | — | WO | disclosed |