Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 4/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | KDM1B | Q8NB78 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ASF1A | Q9Y294 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401125 | 0.80 | ITGB3 (0.51) | MIFITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL7401638 | 0.76 | ITGB3 (0.50) | MIFITGB3ITGA2BKDM1ARCOR1 | |
| SCHEMBL7433070 | 0.75 | ITGB3 (0.68) | MIFITGB3ITGA2B | |
| SCHEMBL7400582 | 0.74 | ITGB3 (0.43) | MIFITGB3ITGA2BKDM1ARCOR1 | |
| SCHEMBL7400579 | 0.74 | ITGB3 (0.43) | MIFITGB3ITGA2BKDM1ARCOR1 | |
| SCHEMBL7396918 | 0.72 | ITGB3 (0.68) | MIFITGB3ITGA2B | |
| SCHEMBL7441463 | 0.72 | MIF (0.40) | MIFITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL7503400 | 0.71 | MIF (0.45) | MIFITGB3ITGA2BKDM1ARCOR1 | |
| SCHEMBL7441471 | 0.70 | MIF (0.40) | MIFITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL7597992 | 0.70 | ITGB3 (0.57) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593603-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| EP-0593603-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-04-27 | — | — | EP | disclosed |
| WO-1993000095-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-07 | — | — | WO | disclosed |