Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10769646 | 0.93 | ENPEP (0.47) | FFAR4FFAR1ALDH1A1GSTK1AKR1B1 | |
| SCHEMBL15956044 | 0.84 | TSHR (0.60) | FFAR4FFAR1ALDH1A1GSTK1ENPEP | |
| SCHEMBL867829 | 0.84 | — | — | |
| SCHEMBL12506523 | 0.83 | FFAR4 (0.69) | FFAR4FFAR1ALDH1A1AKR1B1KMT2A | |
| SCHEMBL21772258 | 0.83 | FFAR4 (0.69) | FFAR4FFAR1ALDH1A1AKR1B1KMT2A | |
| SCHEMBL2349520 | 0.83 | FFAR4 (0.69) | FFAR4FFAR1ALDH1A1AKR1B1KMT2A | |
| SCHEMBL31046957 | 0.83 | ALDH1A1 (0.61) | FFAR4FFAR1ALDH1A1GSTK1AKR1B1 | |
| SCHEMBL12384963 | 0.83 | FFAR4 (0.69) | FFAR4FFAR1ALDH1A1AKR1B1KMT2A | |
| SCHEMBL1516585 | 0.83 | ALDH1A1 (0.61) | FFAR4FFAR1ALDH1A1GSTK1AKR1B1 | |
| SCHEMBL10942819 | 0.83 | FFAR4 (0.69) | FFAR4FFAR1ALDH1A1AKR1B1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0599199-B1 | Silver halide photographic emulsions sensitized in the presence of organic disulfides and sulfinates | EASTMAN KODAK CO (US) | 1997-03-12 | — | — | EP | claimed |
| US-5364754-A | Silver halide photographic emulsions precipitated in the presence of organic dichalcogenides | EASTMAN KODAK COMPANY (US) | 1994-11-15 | — | — | US | claimed |
| US-5328820-A | Precipitation of silver halide, sensitization and adding antifogging agents | EASTMAN KODAK COMPANY (US) | 1994-07-12 | — | — | US | claimed |
| EP-0599199-A1 | Silver halide photographic emulsions sensitized in the presence of organic disulfides and sulfinates | EASTMAN KODAK COMPANY (US) | 1994-06-01 | — | — | EP | claimed |
| EP-0566074-A2 | Silver halide photographic emulsions precipitated in the presence of organic dichalcogenides | EASTMAN KODAK COMPANY (US) | 1993-10-20 | — | — | EP | claimed |
| US-20180305231-A1 | COMPOSITE, A METHOD OF MAKING THEREOF, AND A METHOD FOR DEGRADING A POLLUTANT | KING ABDULAZIZ UNIVERSITY (SA) | 2018-10-25 | — | — | US | disclosed |
| US-9284541-B2 | Methods and compositions for protein labeling using lipoic acid ligases | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-03-15 | — | — | US | disclosed |
| US-8871456-B2 | Probe incorporation mediated by enzymes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-10-28 | — | — | US | disclosed |
| WO-2013052851-A1 | METHODS AND COMPOSITIONS FOR POLYPEPTIDE AND PROTEIN LABELING USING LIPOIC ACID LIGASES SPECIFIC TO RESORUFIN | MASSACHUSETTS INISTITUTE OF TECHNOLOGY (US) | 2013-04-11 | — | — | WO | disclosed |
| US-20120214201-A1 | PROBE INCORPORATION MEDIATED BY ENZYMES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-08-23 | — | — | US | disclosed |
| US-20120129159-A1 | METHODS AND COMPOSITIONS FOR PROTEIN LABELING USING LIPOIC ACID LIGASES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-05-24 | — | — | US | disclosed |
| US-8137925-B2 | Methods and compositions for protein labeling using lipoic acid ligases | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-03-20 | — | — | US | disclosed |
| EP-0599199-B1 | Silver halide photographic emulsions sensitized in the presence of organic disulfides and sulfinates | EASTMAN KODAK CO (US) | 1997-03-12 | — | — | EP | disclosed |
| US-5364754-A | Silver halide photographic emulsions precipitated in the presence of organic dichalcogenides | EASTMAN KODAK COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| EP-0617320-A2 | Tabular grain emulsions containing antifoggants and stabilizers | EASTMAN KODAK COMPANY (US) | 1994-09-28 | — | — | EP | disclosed |
| US-5328820-A | Precipitation of silver halide, sensitization and adding antifogging agents | EASTMAN KODAK COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5320938-A | Occurs in the presence of iodide | EASTMAN KODAK COMPANY (US) | 1994-06-14 | — | — | US | disclosed |
| EP-0599199-A1 | Silver halide photographic emulsions sensitized in the presence of organic disulfides and sulfinates | EASTMAN KODAK COMPANY (US) | 1994-06-01 | — | — | EP | disclosed |
| EP-0566074-A2 | Silver halide photographic emulsions precipitated in the presence of organic dichalcogenides | EASTMAN KODAK COMPANY (US) | 1993-10-20 | — | — | EP | disclosed |
| US-4087282-A | COPOLYMERS OF ISOBUTYLENE AND MALEIC ACID DERIVATIVES | FUJI PHOTO FILM CO., LTD. (JA) | 1978-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129159-A1 | METHODS AND COMPOSITIONS FOR PROTEIN LABELING USING LIPOIC ACID LIGASES | LARS1, ACSL5, RARS1 | FFAR4 3562/4885FFAR1 2922/4885ALDH1A1 1936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.