Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | RXRA | P19793 | 4/20 | 0.48 |
| ▸ | RXRG | P48443 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984662 | 0.84 | RXRB (0.46) | RXRBNAAAALDH1A1NPC1RAB9A | |
| SCHEMBL1466479 | 0.82 | CYP3A4 (0.56) | RXRBCYP3A4NAAAALDH1A1NPC1 | |
| SCHEMBL17013375 | 0.81 | RXRB (0.52) | RXRBNAAAALDH1A1NPC1RAB9A | |
| SCHEMBL17013374 | 0.81 | NAAA (0.56) | RXRBNAAAALDH1A1NPC1RAB9A | |
| SCHEMBL6889767 | 0.80 | RXRB (0.58) | RXRBNAAAALDH1A1NPC1RAB9A | |
| SCHEMBL17356839 | 0.79 | RXRB (0.50) | RXRBNAAAALDH1A1NPC1RAB9A | |
| SCHEMBL31511278 | 0.78 | DRD2 (0.54) | CYP3A4NAAAALDH1A1MAPTHSD17B10 | |
| SCHEMBL16882858 | 0.78 | ALDH1A1 (0.53) | RXRBCYP3A4NAAAALDH1A1NPC1 | |
| SCHEMBL16363617 | 0.77 | NAAA (0.46) | RXRBNAAAALDH1A1NPC1RAB9A | |
| SCHEMBL6660683 | 0.76 | RAB9A (0.51) | RXRBNAAAALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996015099-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1996-05-23 | — | — | WO | disclosed |
| WO-1996015100-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1996-05-23 | — | — | WO | disclosed |