Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.47 |
| ▸ | PTGFR | P43088 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL448011 | 0.79 | TRPA1 (0.56) | PPARGPPARATRPA1 | |
| SCHEMBL5105980 | 0.77 | TRPA1 (0.52) | KDM4EPOLBTRPA1 | |
| SCHEMBL15319795 | 0.77 | IDO1 (0.44) | PTGFRALDH1A1GAAHDAC1HDAC8 | |
| SCHEMBL17671285 | 0.76 | KDM4E (0.54) | PPARGKDM4EALDH1A1ATMPPARA | |
| SCHEMBL13849900 | 0.74 | PPARG (0.45) | PPARGPPARAEPHX2POLBIDO1 | |
| SCHEMBL14402485 | 0.74 | PPARG (0.45) | PPARGPPARAEPHX2POLBIDO1 | |
| SCHEMBL8418978 | 0.73 | IDO1 (0.41) | PTGFRKDM4EALDH1A1ATMGAA | |
| SCHEMBL28702695 | 0.73 | SIGMAR1 (0.52) | — | |
| SCHEMBL17329111 | 0.73 | IDO1 (0.59) | KDM4EALDH1A1ATMPOLBHDAC1 | |
| SCHEMBL8030461 | 0.73 | SLC6A2 (0.48) | KDM4EALDH1A1ATMPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869792-A4 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 1999-09-22 | — | — | EP | claimed |
| EP-0869792-A2 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1998-10-14 | — | — | EP | claimed |
| WO-1997023216-A1 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1997-07-03 | — | — | WO | claimed |