SCHEMBL7401298

SCHEMBL7401298

CC1(CCCCc2ccc(C=NN)cc2)CC(CC(=O)O)CC(=O)O1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.32
PPARG P37231 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8991026 0.76
SCHEMBL7399372 0.75 PRKCA (0.37) PPARAPPARG
SCHEMBL7385516 0.67 MAPT (0.54)
SCHEMBL7398099 0.67 PRKCD (0.35) PPARAPPARG
SCHEMBL7397355 0.63 PRKCA (0.39) PPARG
SCHEMBL7404000 0.63 PRKCD (0.38) PPARG
SCHEMBL8991198 0.63 PPARA (0.32) PPARAPPARG
SCHEMBL7396167 0.61 PRKCA (0.38)
SCHEMBL8991248 0.61 PLA2G6 (0.34)
SCHEMBL11508214 0.60 HTR2A (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994000424-A1 PHENYL AMIDINE ALKANOIC ACIDS AND LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1994-01-06 WO disclosed