Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2674626 | 0.88 | SIGMAR1 (0.43) | SIGMAR1SRD5A1SRD5A2KDM4EALDH1A1 | |
| SCHEMBL28294184 | 0.85 | ALDH1A1 (0.43) | SIGMAR1SRD5A1SRD5A2KDM4EALDH1A1 | |
| SCHEMBL27821528 | 0.85 | NOTUM (0.42) | SIGMAR1SRD5A1SRD5A2KDM4EALDH1A1 | |
| SCHEMBL13090339 | 0.84 | SIGMAR1 (0.47) | SIGMAR1SRD5A1SRD5A2AKR1B1ALDH1A1 | |
| SCHEMBL7825602 | 0.83 | SIGMAR1 (0.49) | SIGMAR1SRD5A1SRD5A2KDM4EALDH1A1 | |
| SCHEMBL1520645 | 0.82 | HTR6 (0.47) | AKR1B1KDM4ELMNA | |
| SCHEMBL30486873 | 0.82 | HTR6 (0.47) | AKR1B1KDM4ELMNA | |
| SCHEMBL7403188 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1HPGDNOTUM | |
| Hydrochloric Acid SCHEMBL30279689 | 0.81 | HTR6 (0.46) | AKR1B1KDM4ELMNA | |
| SCHEMBL3451418 | 0.80 | AKR1B1 (0.56) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2730918-B1 | MATRIX FOR MALDI MASS SPECTROMETRY AND MALDI MASS SPECTROMETRY METHOD | UNIV KYUSHU NAT UNIV CORP (JP) | 2016-09-14 | — | — | EP | disclosed |
| WO-2014109712-A1 | PALLADIUM-CATALYZED ASYMMETRIC (HETERO)ARYLATION AND VINYLATION OF KETONE ENOLATES TO PRODUCE TERTIARY STEREOCENTERS AT ALPHA(α)-POSITION | NANAYNG TECHNOLOGICAL UNIVERSITY (SG) | 2014-07-17 | — | — | WO | disclosed |
| US-20140151548-A1 | MATRIX FOR MALDI MASS SPECTROMETRY AND MALDIMASS SPECTROMETRY METHOD | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| EP-2730918-A1 | MATRIX FOR MALDI MASS SPECTROMETRY | Kyushu University National University Corporation (JP) | 2014-05-14 | — | — | EP | disclosed |
| US-6133446-A | Heterocyclic compounds for the treatment of CNS and cardiovascular disorders | PHARMACIA & UPJOHN COMPANY (US) | 2000-10-17 | — | — | US | disclosed |
| CN-1046507-C | Heterocyclic compounds for the treatment of central nervous system and cardiovascular diseases | UPJOHN CO (US) | 1999-11-17 | — | — | CN | disclosed |
| US-5877317-A | Heterocyclic compounds for the treatment of CNS and cardiovascular disorders | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-02 | — | — | US | disclosed |
| CN-1139431-A | Heterocyclic compounds for the treatment of central nervous system and cardiovascular diseases | PHARMACIA & UPJOHN CO LLC (US) | 1997-01-01 | — | — | CN | disclosed |
| EP-0737189-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF CNS AND CARDIOVASCULAR DISORDERS | PHARMACIA & UPJOHN COMPANY (US) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995018118-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF CNS AND CARDIOVASCULAR DISORDERS | THE UPJOHN COMPANY (US) | 1995-07-06 | — | — | WO | disclosed |
| EP-0287987-A1 | Analgesic and antiinflammatory pharmaceutical compositions containing a naphthyl-acetic acid derivative | L.B.S. S.r.l. LABORATORIO BIOCHIMICO SPERIMENTALE (IT) | 1988-10-26 | — | — | EP | disclosed |
| EP-0287987-A1 | Analgesic and antiinflammatory pharmaceutical compositions containing a naphthyl-acetic acid derivative | L.B.S. S.r.l. LABORATORIO BIOCHIMICO SPERIMENTALE (IT) | 1988-10-26 | — | — | EP | disclosed |