Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7404818 | 0.86 | ALDH1A1 (0.41) | ALDH1A1TSHRCYP3A4LMNAP2RX4 | |
| SCHEMBL7484093 | 0.86 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNAP2RX4RAB9A | |
| SCHEMBL7576541 | 0.84 | TSHR (0.41) | ALDH1A1TSHRCYP3A4LMNAPOLB | |
| SCHEMBL6136648 | 0.81 | MEN1 (0.38) | ALDH1A1CYP3A4LMNAPOLBESR1 | |
| SCHEMBL7237747 | 0.79 | GAA (0.37) | ALDH1A1TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL7879014 | 0.78 | ALDH1A1 (0.38) | ALDH1A1TSHRLMNAADRB2ADRB1 | |
| SCHEMBL7227154 | 0.75 | FSCN1 (0.46) | ALDH1A1TSHRCYP3A4LMNAL3MBTL1 | |
| SCHEMBL8001991 | 0.74 | ALDH1A1 (0.37) | ALDH1A1TSHRLMNARAB9ACYP2C9 | |
| SCHEMBL5897694 | 0.74 | MTNR1A (0.44) | ALDH1A1ESR1 | |
| SCHEMBL7237657 | 0.74 | MEN1 (0.37) | ALDH1A1TSHRLMNAPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942924-A2 | METHODS AND COMPOUNDS FOR INHIBITING $g(b)-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS | Elan Pharmaceuticals, Inc. (US) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998022494-A2 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | ELAN PHARMACEUTICALS, INC. (US) | 1998-05-28 | — | — | WO | disclosed |