Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571655 | 0.86 | TSHR (0.42) | TSHRL3MBTL1TDP1CYP3A4MAPK1 | |
| SCHEMBL7401889 | 0.84 | ALDH1A1 (0.40) | TSHRL3MBTL1CYP3A4ALDH1A1LMNA | |
| SCHEMBL7573230 | 0.82 | TSHR (0.45) | TSHRL3MBTL1TDP1CYP3A4MAPK1 | |
| SCHEMBL6136648 | 0.80 | MEN1 (0.38) | L3MBTL1CYP3A4ALDH1A1LMNARAB9A | |
| SCHEMBL7569876 | 0.80 | FAAH (0.39) | TSHRL3MBTL1TDP1FAAHMAPK1 | |
| SCHEMBL7574293 | 0.78 | LTB4R2 (0.40) | TSHRL3MBTL1TDP1FAAHALDH1A1 | |
| SCHEMBL7567614 | 0.78 | RAB9A (0.34) | TSHRL3MBTL1TDP1ALDH1A1HSD17B10 | |
| SCHEMBL7567342 | 0.76 | CETP (0.40) | TSHRL3MBTL1TDP1CYP3A4MAPK1 | |
| SCHEMBL7570565 | 0.76 | ALDH1A1 (0.47) | TSHRL3MBTL1TDP1MAPK1ALDH1A1 | |
| SCHEMBL7572658 | 0.75 | L3MBTL1 (0.39) | TSHRL3MBTL1TDP1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | disclosed |