Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 12/20 | 0.62 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.55 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.55 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 3/20 | 0.51 |
| ▸ | DRD1 | P21728 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | DRD5 | P21918 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3564031 | 0.80 | LTA4H (0.49) | LTA4HPSMB1PSMB5PSMB2HRH1 | |
| SCHEMBL7398107 | 0.79 | LTA4H (0.63) | LTA4HPSMB1PSMB5PSMB2ESR1 | |
| SCHEMBL7135467 | 0.78 | PSMB1 (0.82) | LTA4HPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL7141059 | 0.77 | LTA4H (1.00) | LTA4HPSMB1PSMB5PSMB2HRH1 | |
| SCHEMBL14397182 | 0.75 | TSHR (0.67) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL4485237 | 0.74 | SMN1; SMN2 (0.51) | LTA4HDRD1DRD3DRD2ESR1 | |
| SCHEMBL2562707 | 0.74 | SMN1; SMN2 (0.55) | LTA4HESR1ESR2SMN1; SMN2 | |
| SCHEMBL3564150 | 0.74 | ALDH1A1 (0.49) | LTA4HESR1ESR2SMN1; SMN2 | |
| SCHEMBL29573150 | 0.73 | TDP1 (0.66) | LTA4HHRH1DRD1DRD4DRD5 | |
| SCHEMBL2557491 | 0.72 | TDP1 (0.52) | LTA4HSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869792-A4 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 1999-09-22 | — | — | EP | claimed |
| EP-0869792-A2 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1998-10-14 | — | — | EP | claimed |
| WO-1997023216-A1 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1997-07-03 | — | — | WO | claimed |