Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GYS1 | P13807 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL740398 | 1.00 | ALDH1A1 (0.36) | ALDH1A1TSHRKMT2AGYS1CTSC | |
| SCHEMBL739855 | 0.87 | PIK3CD (0.37) | CTSCBTKFASN | |
| SCHEMBL739856 | 0.87 | PIK3CD (0.37) | CTSCBTKFASN | |
| SCHEMBL738530 | 0.86 | KMT2A (0.36) | ALDH1A1TSHRKMT2ACTSCBTK | |
| SCHEMBL740270 | 0.86 | KMT2A (0.36) | ALDH1A1TSHRKMT2ACTSCBTK | |
| SCHEMBL738529 | 0.86 | KMT2A (0.36) | ALDH1A1TSHRKMT2ACTSCBTK | |
| SCHEMBL739272 | 0.85 | NPY1R (0.36) | ALDH1A1TSHRKMT2ABTKNPY1R | |
| SCHEMBL739273 | 0.85 | NPY1R (0.36) | ALDH1A1TSHRKMT2ABTKNPY1R | |
| SCHEMBL741986 | 0.85 | SMYD3 (0.35) | ALDH1A1TSHRKMT2ACTSCBTK | |
| SCHEMBL740638 | 0.85 | GSK3B (0.37) | BTKDYRK1ACFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | claimed |
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |