Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 7/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403455 | 0.84 | ITGB3 (0.60) | ITGB3ITGA2BALDH1A1MAPTKDM4E | |
| SCHEMBL7400379 | 0.82 | ITGB3 (0.51) | ITGB3ITGA2BALDH1A1MAPTKDM4E | |
| SCHEMBL7396524 | 0.81 | MEN1 (0.53) | ITGB3ITGA2BALDH1A1KDM4EF10 | |
| SCHEMBL7393627 | 0.78 | HRH3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL7393626 | 0.75 | ITGB3 (0.57) | ITGB3ITGA2BALDH1A1MAPTKDM4E | |
| SCHEMBL7399572 | 0.74 | MAPT (0.46) | ITGB3ITGA2BALDH1A1MAPTKDM4E | |
| SCHEMBL7400469 | 0.74 | TBXA2R (0.45) | ITGB3ITGA2BALDH1A1SMN1; SMN2 | |
| SCHEMBL7402198 | 0.73 | ITGB3 (0.44) | ITGB3ITGA2B | |
| SCHEMBL7402405 | 0.73 | ALDH1A1 (0.53) | ITGB3ITGA2BALDH1A1MAPTKDM4E | |
| SCHEMBL7399968 | 0.73 | HTR1A (0.48) | ITGB3ITGA2BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |