Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7393627 | 0.91 | HRH3 (0.47) | S1PR1HRH3LMNADRD4SLC6A4 | |
| SCHEMBL7398399 | 0.84 | LMNA (0.51) | HRH3LMNASMN1; SMN2HTTTSHR | |
| SCHEMBL8636667 | 0.82 | ITGB3 (0.55) | S1PR1HRH3SLC6A4ITGB3ITGA2B | |
| SCHEMBL7399688 | 0.81 | ALDH1A1 (0.57) | TBXA2RTBXAS1LMNASMN1; SMN2HTT | |
| SCHEMBL7400250 | 0.81 | ITGB3 (0.49) | S1PR1HRH3SLC6A4ITGB3ITGA2B | |
| SCHEMBL7399968 | 0.79 | HTR1A (0.48) | S1PR1HRH3LMNASMN1; SMN2HTT | |
| SCHEMBL9517111 | 0.77 | HRH3 (0.49) | HRH3LMNASMN1; SMN2HTTTSHR | |
| SCHEMBL9080516 | 0.76 | MEN1 (0.50) | HRH3SMN1; SMN2HTTTSHRDRD4 | |
| SCHEMBL7404198 | 0.74 | ITGB3 (0.49) | SMN1; SMN2ITGB3ITGA2BALDH1A1 | |
| SCHEMBL7401837 | 0.73 | TBXA2R (0.49) | TBXA2RTBXAS1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |