Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2088669 | 0.83 | CYP19A1 (0.49) | SLC6A2SLC6A4SLC6A3MTNR1AMTNR1B | |
| SCHEMBL27338429 | 0.82 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3SLC16A3SMN1; SMN2 | |
| SCHEMBL620932 | 0.81 | ENPP2 (0.47) | SLC6A2SLC6A4SLC6A3HPGDS | |
| SCHEMBL31589346 | 0.78 | ENPP2 (0.50) | SLC6A2SLC6A4SLC6A3LMNAKMT2A | |
| SCHEMBL866194 | 0.75 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3SMN1; SMN2OPRK1 | |
| SCHEMBL4748924 | 0.73 | KYNU (0.47) | SLC6A2SLC6A4SLC6A3SMN1; SMN2HPGDS | |
| SCHEMBL28041147 | 0.73 | ESR1 (0.52) | SLC6A2SLC6A4SLC6A3OPRK1ESR1 | |
| SCHEMBL4773619 | 0.73 | CYP19A1 (0.53) | SLC6A2SLC6A4SLC6A3MTNR1AMTNR1B | |
| SCHEMBL4719282 | 0.71 | EPHX1 (0.53) | HPGDSOPRK1LMNA | |
| SCHEMBL28311611 | 0.71 | ENPP2 (0.52) | SLC6A2SLC6A4SLC6A3OPRK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869792-A4 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 1999-09-22 | — | — | EP | claimed |
| EP-0869792-A2 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1998-10-14 | — | — | EP | claimed |
| WO-1997023216-A1 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1997-07-03 | — | — | WO | claimed |