Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.53 |
| ▸ | EDNRA | P25101 | 14/20 | 0.52 |
| ▸ | EDNRB | P24530 | 12/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10420864 | 0.79 | EDNRA (0.48) | EDNRAEDNRB | |
| SCHEMBL6026448 | 0.79 | HSD11B1 (0.56) | SCN9AHSD11B1 | |
| SCHEMBL7947359 | 0.77 | RAB9A (0.43) | SCN9AEDNRAEDNRB | |
| SCHEMBL8694517 | 0.77 | EDNRA (0.56) | EDNRAEDNRBFBP1 | |
| SCHEMBL7508467 | 0.77 | EDNRB (0.50) | EDNRAEDNRB | |
| SCHEMBL4617033 | 0.75 | ALDH1A1 (0.54) | EDNRAEDNRB | |
| SCHEMBL8350452 | 0.73 | EDNRA (0.54) | EDNRAEDNRBFBP1 | |
| SCHEMBL7243371 | 0.72 | EDNRA (0.54) | SCN9AEDNRAEDNRBFBP1 | |
| SCHEMBL7230668 | 0.72 | EDNRA (0.54) | EDNRAEDNRBFBP1 | |
| SCHEMBL7402493 | 0.71 | EDNRA (0.39) | SCN9AEDNRAEDNRBFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921800-A4 | SUBSTITUTED BIPHENYL ISOXAZOLE SULFONAMIDES | BRISTOL MYERS SQUIBB CO (US) | 2000-12-06 | — | — | EP | disclosed |
| EP-0921800-A1 | SUBSTITUTED BIPHENYL ISOXAZOLE SULFONAMIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-06-16 | — | — | EP | disclosed |
| WO-1997029748-A1 | SUBSTITUTED BIPHENYL ISOXAZOLE SULFONAMIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-08-21 | — | — | WO | disclosed |