Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 17/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.32 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.32 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7404661 | 0.78 | ELANE (0.33) | ELANETPSAB1TPSD1TPSG1 | |
| SCHEMBL7407090 | 0.75 | CARM1 (0.35) | ELANE | |
| SCHEMBL7405849 | 0.75 | ELANE (0.33) | ELANE | |
| SCHEMBL8614493 | 0.74 | ELANE (0.42) | ELANETPSAB1TPSD1TPSG1 | |
| SCHEMBL8614366 | 0.71 | ELANE (0.43) | ELANE | |
| SCHEMBL7448574 | 0.69 | CARM1 (0.38) | ELANE | |
| SCHEMBL7407088 | 0.68 | ELANE (0.41) | ELANE | |
| SCHEMBL7280450 | 0.68 | ELANE (0.69) | ELANE | |
| SCHEMBL7008337 | 0.68 | ELANE (0.50) | ELANE | |
| SCHEMBL8615757 | 0.66 | ELANE (0.33) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997010243-A1 | 2-(PYRAZOL-5-YL-OXYMETHYL)-1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI (US) | 1997-03-20 | — | — | WO | disclosed |