Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 2/20 | 0.42 |
| ▸ | CPA3 | P15088 | 2/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7536026 | 1.00 | MMP8 (0.45) | MMP8USP2HTTCYP1A2CPA1 | |
| SCHEMBL7288147 | 0.91 | CPA1 (0.53) | MMP8USP2HTTCYP1A2CPA1 | |
| SCHEMBL7287460 | 0.84 | LIPE (0.52) | MMP8USP2HTTCYP1A2LIPE | |
| SCHEMBL7539288 | 0.81 | FKBP1A (0.56) | MMP8USP2SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7539281 | 0.81 | FKBP1A (0.56) | MMP8USP2SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7281480 | 0.79 | MMP1 (0.43) | MMP8LTA4H | |
| SCHEMBL6754301 | 0.78 | MMP8 (0.50) | MMP8USP2HTTCDK5CDK5R1 | |
| SCHEMBL6754303 | 0.78 | MMP8 (0.50) | MMP8USP2HTTCDK5CDK5R1 | |
| SCHEMBL2680002 | 0.77 | CPA3 (0.55) | MMP8CPA3FOLH1MEN1ALDH1A1 | |
| SCHEMBL6790329 | 0.77 | SMN1; SMN2 (0.59) | USP2HTTCYP1A2LIPECDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416393-A1 | Peptidyl difluorodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |