Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.58 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12743824 | 0.86 | RARB (0.55) | PLA2G4BCYP4F2CYP4A11PKMSMN1; SMN2 | |
| SCHEMBL14966872 | 0.86 | LTA4H (0.56) | PLA2G4BCYP4F2CYP4A11PKMTBXAS1 | |
| SCHEMBL4361279 | 0.85 | PLA2G4B (0.76) | PLA2G4BPKMTP53TSHRFFAR1 | |
| SCHEMBL9042801 | 0.84 | PTPRC (0.53) | PLA2G4BCYP4F2CYP4A11LMNASMN1; SMN2 | |
| SCHEMBL7397574 | 0.84 | MAPT (0.64) | CYP4F2CYP4A11LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5350293 | 0.83 | NAPRT (0.59) | TBXAS1TP53TSHRALDH1A1MEN1 | |
| SCHEMBL10638830 | 0.83 | NAPRT (0.59) | TBXAS1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL18906034 | 0.82 | NR4A2 (0.72) | PLA2G4BSMN1; SMN2 | |
| SCHEMBL14966915 | 0.82 | PKM (0.71) | PLA2G4BCYP4F2CYP4A11PKMTP53 | |
| SCHEMBL9550977 | 0.81 | NPC1 (0.69) | PLA2G4BPKMTP53TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648368-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1997-07-15 | — | — | US | disclosed |
| WO-1994012181-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-09 | — | — | WO | disclosed |