SCHEMBL740548

SCHEMBL740548

CCCc1cc(C)cc(CCc2cc(C)cc(CCC)c2O)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.45
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
HIF1A Q16665 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
ALDH1A1 P00352 3/20 0.42
HTT P42858 1/20 0.42
HSPA5 P11021 1/20 0.41
HMGCR P04035 1/20 0.41
SELL P14151 1/20 0.40
SELP P16109 1/20 0.40
SELE P16581 1/20 0.40
DHFR P00374 1/20 0.37
MAOA P21397 1/20 0.37
PRKCI P41743 1/20 0.37
PTPN1 P18031 1/20 0.37
PTPN11 Q06124 1/20 0.37
NOS3 P29474 1/20 0.36
NOS1 P29475 1/20 0.36
NOS2 P35228 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1021760 0.98 AMY1A (0.47) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL1023654 0.91 DHFR (0.45) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL1987359 0.91 AMY1A (0.57) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL1023112 0.89 TYR (0.46) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL5676839 0.86 SELL (0.54) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL1024995 0.86 ALDH1A1 (0.45) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL280118 0.84 TYR (0.48) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL14032753 0.83 HMGCR (0.40) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL27679370 0.83 ALOX5 (0.40) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL5078445 0.83 TYR (0.53) HTTALOX5TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10428216-B2 Golf ball incorporating a mixture of a thermoset and/or thermoplastic composition and a plurality of conductive nanoshelled structures ACUSHNET COMPANY (US) 2019-10-01 US disclosed
US-20190192922-A1 GOLF BALL COMPRISING MEDIUM HARDNESS GRADIENT CORE ACUSHNET COMPANY (US) 2019-06-27 US disclosed
US-10252115-B2 Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer ACUSHNET COMPANY (US) 2019-04-09 US disclosed
US-10220263-B2 Golf balls comprising medium hardness gradient core ACUSHNET COMPANY (US) 2019-03-05 US disclosed
US-10130848-B2 Golf ball multilayer core having a gradient quotient ACUSHNET COMPANY (US) 2018-11-20 US disclosed
US-20180318654-A1 GOLF BALL INCORPORATING POSITIVE HARDNESS GRADIENT THERMOSET POLYURETHANE OUTER COVER LAYER ACUSHNET COMPANY (US) 2018-11-08 US disclosed
US-10112081-B2 Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer ACUSHNET COMPANY (US) 2018-10-30 US disclosed
US-10035046-B2 Multilayer core golf ball having hardness gradient within and between each core layer ACUSHNET COMPANY (US) 2018-07-31 US disclosed
US-10029151-B2 Multi-layer cover golf ball having a high acid casing layer ACUSHNET COMPANY (US) 2018-07-24 US disclosed
US-10029150-B2 Golf ball having medium positive gradient quotient and low trans content ACUSHNET COMPANY (US) 2018-07-24 US disclosed
US-20090011863-A1 Negative Hardness Gradient Inner Core for Dual Core Golf Ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-01-08 US disclosed
US-20090008832-A1 Negative Hardness Gradient Core Produced from a Low, Temperature-Based Cure Cycle Index ACUSHNET COMPANY 2009-01-08 US disclosed
US-20090011855-A1 Golf Ball Core with Soft Outer Transition Volume and Negative Hardness Gradient ACUSHNET COMPANY 2009-01-08 US disclosed
US-20090011867-A1 Multi-Layer Core Golf Ball Having Opposing Hardness Gradient with Steep Gradient Outer Core Layer JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-01-08 US disclosed
US-20090011866-A1 Multi-Layer Core Golf Ball Having Opposing Hardness Gradient with Steep Gradient Inner Core Layer JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-01-08 US disclosed
US-7429221-B1 Negative hardness gradient outer core layer for dual core golf ball ACUSHNET COMPANY (US) 2008-09-30 US disclosed
US-7410429-B1 Negative hardness gradient inner core for dual core golf ball ACUSHNET COMPANY (US) 2008-08-12 US disclosed
US-20080153629-A1 Thick Outer Cover Layer Golf Ball ACUSHNET COMPANY 2008-06-26 US disclosed
US-20080146380-A1 Thick Outer Cover Layer Golf Ball ACUSHNET COMPANY 2008-06-19 US disclosed
US-20080146378-A1 Thick Inner Cover Multi-layer Golf Ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2008-06-19 US disclosed