Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | WEE1 | P30291 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10988698 | 0.80 | MAPT (0.43) | FABP4FABP5FABP3KDM4EPOLB | |
| SCHEMBL7415741 | 0.75 | WEE1 (0.44) | FABP4FABP5FABP3KDM4EPOLB | |
| SCHEMBL10621833 | 0.72 | KMO (0.57) | FABP4FABP5FABP3KDM4EPOLB | |
| SCHEMBL7414012 | 0.72 | KMO (0.43) | FABP4FABP5FABP3KDM4EPOLB | |
| Iodide SCHEMBL7407059 | 0.72 | KDM4E (0.40) | FABP4FABP5FABP3KDM4EPOLB | |
| Iodide SCHEMBL10619045 | 0.71 | KMO (0.56) | FABP4FABP5FABP3KDM4EPOLB | |
| Iodide SCHEMBL7417715 | 0.70 | KMO (0.39) | FABP4FABP5FABP3KDM4EPOLB | |
| Iodide SCHEMBL7409525 | 0.69 | CASR (0.37) | FABP4FABP5FABP3KDM4EPOLB | |
| SCHEMBL10747226 | 0.69 | TBXAS1 (0.42) | FABP4FABP5FABP3KDM4EPOLB | |
| SCHEMBL10968401 | 0.68 | DYRK1A (0.41) | FABP4FABP5FABP3KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0107398-B1 | ORTHO SUBSTITUTED DIHYDROXY-2(1H)QUINAZOLINONE-1-ALKANOIC ACIDS | ORTHO PHARMA CORP (US) | 1988-06-08 | — | — | EP | claimed |
| US-4631283-A | RENAL VASODILATORS, CARDIOVASCULAR AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-12-23 | — | — | US | claimed |
| EP-0107398-A1 | Ortho substituted dihydroxy-2(1H)quinazolinone-1-alkanoic acids | ORTHO PHARMACEUTICAL CORPORATION (US) | 1984-05-02 | — | — | EP | claimed |