Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7406790 | 0.99 | TMEM97 (0.40) | TMEM97SIGMAR1GRIN2BDRD2DRD3 | |
| SCHEMBL7407950 | 0.87 | TMEM97 (0.39) | TMEM97SIGMAR1GRIN2BPOLBKMT2A | |
| SCHEMBL7411050 | 0.82 | GRIN2B (0.47) | TMEM97SIGMAR1GRIN2BDRD2DRD3 | |
| SCHEMBL7410643 | 0.82 | DRD2 (0.44) | DRD2DRD3 | |
| SCHEMBL7416195 | 0.80 | RB1 (0.41) | TMEM97SIGMAR1GRIN2BDRD2DRD3 | |
| SCHEMBL7408795 | 0.80 | VPS4B (0.36) | TMEM97SIGMAR1GRIN2BPOLBKMT2A | |
| SCHEMBL7404555 | 0.77 | DRD2 (0.39) | GRIN2BDRD2DRD3POLBKMT2A | |
| SCHEMBL7657081 | 0.77 | EGFR (0.52) | TMEM97SIGMAR1DRD2SLC6A4 | |
| SCHEMBL7414233 | 0.76 | JAK2 (0.39) | SIGMAR1GRIN2B | |
| Hydrochloric Acid SCHEMBL7662518 | 0.76 | EGFR (0.54) | TMEM97DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |