Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VPS4B | O75351 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | RB1 | P06400 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.32 |
| ▸ | HTR1B | P28222 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7407950 | 0.90 | TMEM97 (0.39) | VPS4BVCPPOLBKMT2AGRIN2B | |
| SCHEMBL7416195 | 0.89 | RB1 (0.41) | VPS4BVCPPOLBKMT2AGRIN2B | |
| SCHEMBL7411050 | 0.87 | GRIN2B (0.47) | POLBKMT2AGRIN2BRB1TMEM97 | |
| SCHEMBL7404555 | 0.86 | DRD2 (0.39) | POLBKMT2AGRIN2BHTR1DHTR1B | |
| SCHEMBL7409894 | 0.82 | HTR1D (0.46) | POLBKMT2AHTR1DHTR1B | |
| SCHEMBL7402703 | 0.81 | HTR1A (0.35) | VPS4BVCPHTR1ASLC6A4TMEM97 | |
| SCHEMBL7403611 | 0.80 | POLB (0.35) | POLBKMT2AHTR1A | |
| SCHEMBL7407184 | 0.80 | TMEM97 (0.41) | POLBKMT2AGRIN2BSLC6A4TMEM97 | |
| SCHEMBL7414233 | 0.79 | JAK2 (0.39) | GRIN2BSIGMAR1 | |
| SCHEMBL7413287 | 0.79 | APOL1 (0.37) | HTR1ASLC6A4TMEM97HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |