Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | DRD3 | P35462 | 5/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | RB1 | P06400 | 2/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11338802 | 0.90 | MTNR1A (0.42) | DRD2DRD3RB1 | |
| SCHEMBL7413287 | 0.82 | APOL1 (0.37) | DRD2DRD3DRD4HTR1AHTR1D | |
| SCHEMBL7407184 | 0.82 | TMEM97 (0.41) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7406790 | 0.81 | TMEM97 (0.40) | DRD2DRD3 | |
| SCHEMBL7409813 | 0.81 | MTNR1A (0.47) | RB1HTR1AHTR1DHTR1B | |
| SCHEMBL7416460 | 0.79 | RB1 (0.57) | RB1NR2E1HTR1AHTR1DHTR1B | |
| SCHEMBL20542229 | 0.76 | NR2E1 (0.60) | DRD2DRD3MAPK10RIPK1NR2E1 | |
| SCHEMBL7413545 | 0.75 | HTR1A (0.47) | HTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7408528 | 0.74 | HTR1A (0.46) | HTR1AHTR1DHTR1B | |
| SCHEMBL7406537 | 0.72 | CGAS (0.42) | DRD2DRD3DRD4HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |