Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GBA1 | P04062 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517695 | 0.81 | NPC1 (0.55) | NPC1RAB9AMEN1KMT2ACHRNB2 | |
| SCHEMBL31393753 | 0.80 | CHRNB2 (0.78) | NPC1RAB9AKMT2ACHRNB2CHRNB4 | |
| SCHEMBL7372972 | 0.77 | CHRNB2 (0.63) | NPC1RAB9AMEN1KMT2ACHRNB2 | |
| SCHEMBL8614650 | 0.77 | KMT2A (0.58) | MEN1KMT2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6795782 | 0.76 | FFAR1 (0.67) | NPC1RAB9AMEN1KMT2ACHRNB2 | |
| SCHEMBL16900376 | 0.76 | RAB9A (1.00) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL5969191 | 0.76 | RAB9A (0.88) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL8816782 | 0.76 | CHRNB2 (0.54) | MEN1KMT2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL25815514 | 0.75 | NPC1 (0.71) | NPC1RAB9AMEN1KMT2ATRPV1 | |
| SCHEMBL16589432 | 0.75 | PTPN1 (0.80) | NPC1RAB9ATRPV1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |