Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416030 | 0.86 | KMT2A (0.50) | CREBBPCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL7410953 | 0.85 | ALDH1A1 (0.47) | NR1H4KMT2AMEN1POLBMAPT | |
| SCHEMBL7407271 | 0.84 | F10 (0.51) | KMT2AMEN1LMNAPOLBGAA | |
| SCHEMBL8417467 | 0.82 | KMT2A (0.53) | CHEK1PIM1MAPK8CLK4KMT2A | |
| SCHEMBL7408701 | 0.81 | KMT2A (0.43) | CREBBPCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL7411939 | 0.80 | MEN1 (0.60) | KMT2AMEN1GAAMAPTF10 | |
| SCHEMBL8414166 | 0.78 | CHEK1 (0.51) | CHEK1PIM1MAPK8CLK4KMT2A | |
| SCHEMBL7413259 | 0.78 | MEN1 (0.56) | CREBBPPPARGPPARANR1H4KMT2A | |
| SCHEMBL7460237 | 0.77 | NR1H4 (0.47) | PPARGNR1H4KMT2AMEN1RAB9A | |
| SCHEMBL7407140 | 0.76 | PLAU (0.50) | KMT2AMEN1LMNAPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999042439-A1 | NOVEL THIOBENZAMIDES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-26 | — | — | WO | claimed |
| WO-1999042439-A1 | NOVEL THIOBENZAMIDES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-26 | — | — | WO | disclosed |
| EP-0937711-A1 | Thiobenzamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-08-25 | — | — | EP | disclosed |