Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 12/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406891 | 0.89 | DRD2 (0.48) | HTR6KDM1A | |
| SCHEMBL7412957 | 0.83 | DRD2 (0.52) | HTR6PTGDR2 | |
| SCHEMBL7409383 | 0.75 | HTR6 (0.52) | HTR6PTGDR2 | |
| SCHEMBL7412833 | 0.75 | AKR1C3 (0.42) | HTR6PTGDR2 | |
| SCHEMBL7407550 | 0.75 | PKM (0.39) | HTR6 | |
| SCHEMBL7410795 | 0.74 | HTR6 (0.51) | HTR6PTGDR2 | |
| SCHEMBL7408143 | 0.74 | SCARB1 (0.52) | HTR6 | |
| SCHEMBL7416712 | 0.73 | DRD2 (0.53) | HTR6PTGDR2 | |
| SCHEMBL7412095 | 0.73 | HTR6 (0.39) | HTR6PTGDR2 | |
| SCHEMBL7407733 | 0.72 | DRD2 (0.49) | HTR6PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |