Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 4/20 | 0.36 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406891 | 0.76 | DRD2 (0.48) | L3MBTL1HTR6 | |
| SCHEMBL7407295 | 0.75 | HTR6 (0.52) | HTR6PTGDR2 | |
| SCHEMBL7403493 | 0.74 | KMT2A (0.45) | KDM4EALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL7407550 | 0.73 | PKM (0.39) | KDM4EALDH1A1POLBSMN1; SMN2HTR6 | |
| SCHEMBL7517357 | 0.67 | HTR6 (0.57) | AKR1C3AKR1C2HTR6PTGDR2 | |
| SCHEMBL7416472 | 0.66 | PTGS1 (0.40) | HTR6PTGDR2 | |
| SCHEMBL12125729 | 0.64 | KMT2A (0.64) | TRPV4ALDH1A1POLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL7412588 | 0.63 | CYP2C9 (0.56) | KDM4EALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL7413011 | 0.63 | PTGDR2 (0.46) | KDM4EALDH1A1CYP2C9HTR2AKCNH2 | |
| Hydrochloric Acid SCHEMBL7452433 | 0.62 | PTGDR2 (0.45) | KDM4EALDH1A1CYP2C9HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |