Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411751 | 0.77 | MDM2 (0.33) | CHRNA7SLC6A2SLC6A3 | |
| SCHEMBL8324891 | 0.76 | OPRM1 (0.36) | CHRNA7SLC6A2SLC6A3 | |
| SCHEMBL8324893 | 0.68 | KDM4E (0.41) | — | |
| SCHEMBL7405440 | 0.68 | — | — | |
| SCHEMBL16148375 | 0.68 | MEN1 (0.33) | — | |
| SCHEMBL27796397 | 0.68 | ALDH1A1 (0.38) | — | |
| SCHEMBL27260297 | 0.65 | USP19 (0.36) | SLC6A3 | |
| SCHEMBL5431657 | 0.65 | TAAR1 (0.45) | SLC6A2SLC6A3 | |
| SCHEMBL6191840 | 0.65 | TAAR1 (0.32) | — | |
| SCHEMBL20825893 | 0.65 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112251-A1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015609-A1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA S.A. (FR) | 2000-03-23 | — | — | WO | disclosed |