Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 7/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321301 | 0.87 | HPGDS (0.43) | KDM4EMEN1GAAKMT2APRCP | |
| SCHEMBL8318902 | 0.86 | ALDH1A1 (0.47) | KDM4EGAAKMT2APOLBS1PR2 | |
| SCHEMBL1732731 | 0.76 | CNR1 (0.59) | KDM4EMEN1GAAKMT2AHSP90AA1 | |
| SCHEMBL8324891 | 0.74 | OPRM1 (0.36) | MAPK1S1PR3 | |
| SCHEMBL8317963 | 0.73 | S1PR2 (0.44) | KDM4EMEN1GAAKMT2AS1PR2 | |
| SCHEMBL2934366 | 0.72 | SRC (0.46) | MEN1GAAKMT2AMAPK1 | |
| SCHEMBL27260297 | 0.71 | USP19 (0.36) | KDM4EGAAMAPK1 | |
| SCHEMBL8317996 | 0.69 | TP53 (0.46) | — | |
| SCHEMBL27796397 | 0.68 | ALDH1A1 (0.38) | KDM4EMEN1KMT2A | |
| SCHEMBL7407356 | 0.68 | CHRNA7 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071401-A2 | HYDROXAMIC ACID DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS (HDCA) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |