Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 19/20 | 0.67 |
| ▸ | CTSL | P07711 | 9/20 | 0.61 |
| ▸ | CTSS | P25774 | 7/20 | 0.61 |
| ▸ | CTSB | P07858 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406523 | 0.94 | CTSK (0.64) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7520155 | 0.91 | UTS2R (0.61) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7403794 | 0.87 | UTS2R (0.55) | CTSK | |
| SCHEMBL14362856 | 0.85 | CTSK (0.67) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4316252 | 0.83 | CTSK (0.70) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5528745 | 0.82 | CTSK (0.65) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7415020 | 0.82 | UTS2R (0.62) | — | |
| SCHEMBL7400619 | 0.82 | UTS2R (0.62) | — | |
| SCHEMBL7402928 | 0.82 | UTS2R (0.62) | — | |
| SCHEMBL5122686 | 0.81 | TGM2 (0.67) | CTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369077-B1 | OSTEOPOROSIS, PERIODONTITIS, AND ARTHRITIS | SMITHKLINE BEECHAM CORPORATION | 2002-04-09 | — | — | US | claimed |
| EP-0991753-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2001-07-11 | — | — | EP | claimed |
| EP-0991753-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-04-12 | — | — | EP | claimed |
| WO-1998050534-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-12 | — | — | WO | claimed |
| US-6369077-B1 | OSTEOPOROSIS, PERIODONTITIS, AND ARTHRITIS | SMITHKLINE BEECHAM CORPORATION | 2002-04-09 | — | — | US | disclosed |
| EP-0991753-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2001-07-11 | — | — | EP | disclosed |
| EP-0991753-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998050534-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-12 | — | — | WO | disclosed |