SCHEMBL7408673

SCHEMBL7408673

CCc1ccccc1-n1c2c(c3cc(Cc4ccccc4)ccc31)CC(N(C)C)CC2

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 17/20 0.45
PTGDR2 Q9Y5Y4 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7412979 0.89 DRD2 (0.35) HTR6PTGDR2
SCHEMBL7408670 0.78 HTR6 (0.48) HTR6PTGDR2
SCHEMBL7415450 0.69 HTR1F (0.50) HTR6
SCHEMBL8578008 0.66 HTR6 (0.45) HTR6PTGDR2
SCHEMBL7411175 0.66 HTR6 (0.57) HTR6PTGDR2
SCHEMBL7412976 0.65 DRD2 (0.51) HTR6PTGDR2
SCHEMBL7410208 0.65 HTR6 (0.64) HTR6PTGDR2
SCHEMBL7409349 0.65 HTR6 (0.56) HTR6PTGDR2
Hydrochloric Acid SCHEMBL7413394 0.64 HTR6 (0.62) HTR6PTGDR2
SCHEMBL7410597 0.64 HTR6 (0.57) HTR6PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4257952-A PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES STERLING DRUG INC. (US) 1981-03-24 US disclosed
US-4172834-A ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS STERLING DRUG INC. (US) 1979-10-30 US disclosed
US-4062864-A ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE STERLING DRUG INC. (US) 1977-12-13 US disclosed
US-3959309-A ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE STERLING DRUG INC. (US) 1976-05-25 US disclosed