Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 4/20 | 0.48 |
| ▸ | IGF1R | P08069 | 4/20 | 0.48 |
| ▸ | FLT4 | P35916 | 4/20 | 0.48 |
| ▸ | KDR | P35968 | 4/20 | 0.48 |
| ▸ | HTR6 | P50406 | 9/20 | 0.47 |
| ▸ | HRH1 | P35367 | 8/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408670 | 0.87 | HTR6 (0.48) | DRD2EGFRIGF1RFLT4KDR | |
| SCHEMBL7412979 | 0.77 | DRD2 (0.35) | DRD2DRD3EGFRIGF1RFLT4 | |
| SCHEMBL7411294 | 0.76 | DRD3 (0.58) | DRD2DRD3HTR6ADRA2AADRA1A | |
| SCHEMBL7413558 | 0.75 | HRH1 (0.42) | DRD2EGFRIGF1RFLT4KDR | |
| SCHEMBL13887068 | 0.73 | HTR6 (0.66) | DRD2HTR6HRH1ADRA2AHTR2A | |
| SCHEMBL7408712 | 0.73 | HTR6 (0.42) | DRD2EGFRIGF1RFLT4KDR | |
| SCHEMBL7409349 | 0.73 | HTR6 (0.56) | DRD2DRD3HTR6HRH1ADRA2A | |
| SCHEMBL7413587 | 0.71 | CA1 (0.57) | DRD2DRD3HTR6ADRA2AADRA1A | |
| SCHEMBL7410175 | 0.71 | DRD2 (0.58) | DRD2DRD3HTR6HRH1ADRA2A | |
| SCHEMBL7410052 | 0.69 | DRD2 (0.65) | DRD2DRD3HTR6HRH1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |