Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | HTR1F | P30939 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 3/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408264 | 0.90 | HTR6 (0.36) | LMNACHRM3HTR1FACHECHRM2 | |
| SCHEMBL7408867 | 0.88 | CYP2A13 (0.39) | LMNACHRM3HTR1FACHECHRM2 | |
| SCHEMBL7403774 | 0.86 | DRD2 (0.42) | LMNAHTR7DRD2 | |
| SCHEMBL7410521 | 0.82 | HTR1F (0.41) | LMNACHRM3HTR1FCHRM2CHRM1 | |
| SCHEMBL7407854 | 0.82 | CHRM3 (0.44) | CHRM3HTR1FCHRM2CHRM1HTR1A | |
| SCHEMBL7412099 | 0.81 | CHRM3 (0.40) | CHRM3HTR1FCHRM2CHRM1HTR1A | |
| Hydrochloric Acid SCHEMBL7407442 | 0.81 | HTR1F (0.41) | LMNACHRM3HTR1FCHRM2CHRM1 | |
| SCHEMBL7408387 | 0.79 | HTR6 (0.40) | LMNAACHEHTR1AHTR7DRD2 | |
| SCHEMBL7411548 | 0.77 | HRH3 (0.40) | CHRM3HTR1FPARP1 | |
| SCHEMBL7408892 | 0.75 | CHRM3 (0.43) | CHRM3HTR1FCHRM2CHRM1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |