Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.42 |
| ▸ | DRD3 | P35462 | 9/20 | 0.42 |
| ▸ | DRD4 | P21917 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408867 | 0.87 | CYP2A13 (0.39) | DRD2LMNAKDM4EALDH1A1 | |
| SCHEMBL7408264 | 0.87 | HTR6 (0.36) | DRD2LMNAKDM4EALDH1A1HTT | |
| SCHEMBL7409054 | 0.86 | LMNA (0.39) | DRD2LMNAHTR7 | |
| SCHEMBL7408387 | 0.81 | HTR6 (0.40) | DRD2DRD3DRD4LMNAKDM4E | |
| SCHEMBL7412571 | 0.79 | ALDH1A1 (0.46) | LMNAKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7407854 | 0.79 | CHRM3 (0.44) | DRD2DRD3DRD4HTR7 | |
| SCHEMBL7410521 | 0.79 | HTR1F (0.41) | LMNAALDH1A1HTR7 | |
| SCHEMBL7412099 | 0.78 | CHRM3 (0.40) | DRD2DRD3DRD4HTR7 | |
| Hydrochloric Acid SCHEMBL7407442 | 0.78 | HTR1F (0.41) | LMNAALDH1A1HTR7 | |
| SCHEMBL7412016 | 0.72 | HTR1F (0.40) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |