Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419881 | 0.76 | HTR2A (0.41) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7411353 | 0.74 | RPS6KB1 (0.40) | DPP4DPP8DPP9DPP7SLC6A3 | |
| Hydrochloric Acid SCHEMBL7410401 | 0.74 | MC4R (0.40) | RPS6KB1F10 | |
| SCHEMBL7410923 | 0.74 | HTR2A (0.45) | SLC6A2 | |
| SCHEMBL7417965 | 0.73 | HTR2A (0.45) | — | |
| SCHEMBL7411477 | 0.73 | HTR2A (0.45) | — | |
| SCHEMBL7415806 | 0.73 | HTR2A (0.49) | — | |
| SCHEMBL7416307 | 0.73 | HTR2A (0.40) | SLC6A4SLC6A3RPS6KB1 | |
| Hydrochloric Acid SCHEMBL7415163 | 0.72 | SLC6A3 (0.55) | SLC6A4SLC6A3ALDH1A1KDM4EACHE | |
| SCHEMBL7412633 | 0.72 | CYP11B2 (0.42) | RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |