Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411261 | 0.81 | SLC6A3 (0.46) | SLC6A3SMN1; SMN2MAPTEPHX2DPP4 | |
| SCHEMBL7418439 | 0.79 | HSD11B1 (0.55) | MAPTKMT2APTPN1 | |
| SCHEMBL7415265 | 0.78 | GLA (0.54) | SLC6A3SMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL7415806 | 0.77 | HTR2A (0.49) | HTR2AHTR2CHTR7 | |
| Hydrochloric Acid SCHEMBL7410401 | 0.76 | MC4R (0.40) | RPS6KB1F10MAPTHDAC6 | |
| SCHEMBL7410923 | 0.76 | HTR2A (0.45) | HTR2AHTR2CHTR7KCNH2 | |
| SCHEMBL7417965 | 0.75 | HTR2A (0.45) | HTR2AHTR2CHTR7 | |
| SCHEMBL7416307 | 0.75 | HTR2A (0.40) | RPS6KB1SLC6A3HTR2AHTR2CHTR7 | |
| SCHEMBL7412633 | 0.74 | CYP11B2 (0.42) | RPS6KB1HDAC6 | |
| SCHEMBL7409088 | 0.74 | DPP4 (0.47) | RPS6KB1F10SLC6A3DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |