Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 8/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413844 | 0.86 | ACACB (0.35) | GHSRRORCACACBABL1 | |
| SCHEMBL8554626 | 0.79 | IRAK4 (0.39) | — | |
| SCHEMBL7412888 | 0.79 | CHRNB2 (0.49) | — | |
| SCHEMBL7412785 | 0.79 | CHRNB2 (0.49) | — | |
| Hydrochloric Acid SCHEMBL7417419 | 0.78 | IRAK4 (0.39) | — | |
| Hydrochloric Acid SCHEMBL7413921 | 0.78 | CHRNB2 (0.40) | — | |
| SCHEMBL7414891 | 0.77 | CHRNB2 (0.40) | — | |
| SCHEMBL8554428 | 0.76 | CHRNA3 (0.34) | — | |
| SCHEMBL8507798 | 0.75 | VNN1 (0.31) | — | |
| SCHEMBL7408464 | 0.74 | CHRNA3 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047690-A1 | HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 2000-11-02 | — | — | EP | claimed |
| WO-1999032480-A1 | HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1999-07-01 | — | — | WO | claimed |