Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2762012 | 0.89 | SIGMAR1 (0.41) | SMN1; SMN2L3MBTL1SIGMAR1OPRM1KCNH2 | |
| SCHEMBL3979406 | 0.87 | L3MBTL1 (0.37) | SMN1; SMN2L3MBTL1SIGMAR1OPRM1KCNH2 | |
| SCHEMBL2242524 | 0.81 | KMT2A (0.36) | SMN1; SMN2KMT2ACYP3A4HTT | |
| SCHEMBL741073 | 0.77 | L3MBTL1 (0.42) | SMN1; SMN2L3MBTL1SIGMAR1OPRM1KCNH2 | |
| SCHEMBL15710921 | 0.72 | SMN1; SMN2 (0.40) | SMN1; SMN2L3MBTL1SIGMAR1OPRM1KCNH2 | |
| SCHEMBL741114 | 0.72 | L3MBTL1 (0.38) | SMN1; SMN2L3MBTL1SIGMAR1OPRM1KCNH2 | |
| SCHEMBL2762013 | 0.72 | SIGMAR1 (0.39) | SMN1; SMN2L3MBTL1SIGMAR1OPRM1KCNH2 | |
| SCHEMBL741181 | 0.70 | POLB (0.40) | SMN1; SMN2L3MBTL1SIGMAR1POLBPLA2G10 | |
| SCHEMBL740806 | 0.68 | POLB (0.39) | SMN1; SMN2L3MBTL1SIGMAR1OPRM1KCNH2 | |
| SCHEMBL10073915 | 0.66 | FFAR4 (0.41) | L3MBTL1SIGMAR1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138352-B2 | Method for producing asymmetric tetrasubstituted carbon atom-containing compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20110144339-A1 | METHOD FOR PRODUCING ASYMMETRIC TETRASUBSTITUTED CARBON ATOM-CONTAINING COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-06-16 | — | — | US | disclosed |
| US-7928232-B2 | Method for producing asymmetric tetrasubstituted carbon atom-containing compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144339-A1 | METHOD FOR PRODUCING ASYMMETRIC TETRASUBSTITUTED CARBON ATOM-CONTAINING COMPOUND | ACSL3, NQO2, COASY | SMN1; SMN2 4443/4885L3MBTL1 4479/4885SIGMAR1 2640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.