Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 13/20 | 0.48 |
| ▸ | MMP1 | P03956 | 11/20 | 0.48 |
| ▸ | MMP3 | P08254 | 11/20 | 0.47 |
| ▸ | MMP9 | P14780 | 10/20 | 0.47 |
| ▸ | MMP7 | P09237 | 10/20 | 0.47 |
| ▸ | MMP2 | P08253 | 10/20 | 0.47 |
| ▸ | MMP8 | P22894 | 9/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7253756 | 0.88 | MMP1 (0.61) | MMP13MMP1MMP3MMP9MMP7 | |
| SCHEMBL7250977 | 0.87 | MMP13 (0.60) | MMP13MMP1MMP3MMP9MMP7 | |
| SCHEMBL7250907 | 0.87 | MMP13 (0.60) | MMP13MMP1MMP3MMP9MMP7 | |
| SCHEMBL7255621 | 0.85 | MMP13 (0.61) | MMP13MMP1MMP3MMP9MMP7 | |
| SCHEMBL7252096 | 0.85 | ALDH1A1 (0.59) | MMP13MMP1MMP3MMP9MMP7 | |
| SCHEMBL7251763 | 0.84 | MMP1 (0.52) | MMP13MMP1MMP3MMP9MMP7 | |
| SCHEMBL7251813 | 0.83 | MMP13 (0.55) | MMP13MMP1MMP3MMP9MMP7 | |
| SCHEMBL6964392 | 0.82 | MMP1 (0.56) | MMP13MMP1MMP3MMP9MMP7 | |
| SCHEMBL5674362 | 0.81 | USP2 (0.56) | MMP13MMP1MMP3MMP9MMP7 | |
| SCHEMBL7251370 | 0.81 | MMP1 (0.61) | MMP13MMP1MMP3MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265863-A1 | HETEROCYCLIC SIDE CHAIN CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001070690-A1 | HETEROCYCLIC SIDE CHAIN CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2001-09-27 | — | — | WO | disclosed |