Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374857 | 0.91 | GAA (0.40) | SMN1; SMN2GAAHTTKMT2ANPSR1 | |
| SCHEMBL7379148 | 0.78 | PSMD14 (0.40) | SMN1; SMN2HTTALDH1A1POLBKDM4E | |
| SCHEMBL7559581 | 0.78 | NPC1 (0.45) | NR1H4SMN1; SMN2GAAHTTKMT2A | |
| SCHEMBL7407222 | 0.76 | KDM4E (0.40) | SMN1; SMN2GAAHTTKMT2AALDH1A1 | |
| SCHEMBL7378397 | 0.74 | SIRT5 (0.39) | SMN1; SMN2GAAHTTALDH1A1POLB | |
| SCHEMBL7372340 | 0.72 | SIRT5 (0.41) | ALDH1A1POLB | |
| SCHEMBL7377978 | 0.71 | KCNK3 (0.40) | SMN1; SMN2GAAHTTPOLBKDM4E | |
| SCHEMBL7243478 | 0.71 | CYP11B1 (0.40) | SMN1; SMN2GAAHTTKMT2ANPSR1 | |
| SCHEMBL7412126 | 0.70 | DPP4 (0.39) | GAAMAPTPOLBTP53TAAR1 | |
| SCHEMBL7238599 | 0.69 | ALDH1A1 (0.44) | SMN1; SMN2HTTALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002002557-A2 | 2-PHENYLIMIDAZO[1,2-A]PYRIDINE DERIVATIVES: A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 2002-01-10 | — | — | WO | claimed |