Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL110066 | 0.85 | — | — | |
| SCHEMBL16471260 | 0.85 | — | — | |
| SCHEMBL2692924 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL203271 | 0.83 | KIF11 (0.42) | KIF11METAP2METAP1ALDH1A1SLC1A1 | |
| Hydrochloric Acid SCHEMBL2132352 | 0.83 | KIF11 (0.42) | KIF11METAP2METAP1ALDH1A1SLC1A1 | |
| Hydrochloric Acid SCHEMBL203270 | 0.83 | KIF11 (0.42) | KIF11METAP2METAP1ALDH1A1SLC1A1 | |
| SCHEMBL7330937 | 0.81 | NOS1 (0.36) | — | |
| SCHEMBL14844667 | 0.78 | ALDH1A1 (0.41) | ALDH1A1SOAT1 | |
| SCHEMBL8936197 | 0.78 | ANPEP (0.41) | — | |
| SCHEMBL4660348 | 0.77 | PTGS1 (0.44) | SLC1A1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900210-A1 | ANTIVIRALLY ACTIVE HETEROCYCLIC AZAHEXANE DERIVATIVES | Novartis AG (CH) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997040029-A1 | ANTIVIRALLY ACTIVE HETEROCYCLIC AZAHEXANE DERIVATIVES | NOVARTIS AG (CH) | 1997-10-30 | — | — | WO | disclosed |