Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.60 |
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | CCR3 | P51677 | 7/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412259 | 0.88 | MCHR1 (0.71) | MCHR1CCR3HTR2A | |
| SCHEMBL6210244 | 0.77 | HTR2A (0.69) | MCHR1CCR3HTR2A | |
| SCHEMBL7417801 | 0.77 | MCHR1 (0.68) | MCHR1CCR3HTR2A | |
| SCHEMBL7415439 | 0.76 | MCHR1 (0.72) | MCHR1CCR3HTR2A | |
| SCHEMBL7414680 | 0.75 | DRD4 (0.66) | MCHR1HTR2A | |
| SCHEMBL7418001 | 0.74 | SLC18A3 (0.73) | HTR2A | |
| SCHEMBL7412406 | 0.74 | MEN1 (0.66) | MCHR1CCR3 | |
| SCHEMBL1431310 | 0.73 | ACHE (0.61) | HTR2APOLB | |
| SCHEMBL4795270 | 0.73 | S1PR5 (0.62) | MCHR1CCR3POLB | |
| SCHEMBL4795273 | 0.73 | S1PR5 (0.62) | MCHR1CCR3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |