Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410103 | 0.87 | NPC1 (0.45) | ADCY10NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL5823862 | 0.83 | TAAR1 (0.46) | ADCY10NPC1RAB9AL3MBTL1TSHR | |
| SCHEMBL4863794 | 0.79 | NPC1 (0.57) | NPC1RAB9ALMNAL3MBTL1MAPK1 | |
| SCHEMBL5435256 | 0.77 | TAAR1 (0.45) | ADCY10LMNACYP3A4TSHRPOLB | |
| SCHEMBL27497851 | 0.73 | ADCY10 (0.41) | ADCY10NPC1RAB9AL3MBTL1TSHR | |
| SCHEMBL7408080 | 0.73 | NPC1 (0.40) | ADCY10NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL5739505 | 0.72 | CYP2A6 (0.50) | SLC6A3 | |
| SCHEMBL28524683 | 0.72 | CYP2C9 (0.42) | ADCY10LMNATSHRSMN1; SMN2TAAR1 | |
| SCHEMBL5006969 | 0.72 | CYP3A4 (0.62) | ALDH1A1CYP3A4TSHRSMN1; SMN2ALOX15 | |
| SCHEMBL11314534 | 0.72 | L3MBTL1 (0.46) | ADCY10NPC1RAB9ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962248-A | PROCESS FOR MAKING 11-PIPERAZINO-DIAZEPINES, OXAZEPINES, THIAZEPINES AND AZEPINES | SANDOZ, INC. (US) | 1976-06-08 | — | — | US | disclosed |