Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 7/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23752319 | 0.78 | F11 (0.44) | F10PRSS1F2CTSKHSPA9 | |
| SCHEMBL8797898 | 0.76 | PLA2G4A (0.52) | HDAC3HDAC1ALDH1A1PLA2G4A | |
| SCHEMBL24131682 | 0.76 | F10 (0.41) | F10PRSS1F2CTSKF11 | |
| SCHEMBL22851086 | 0.74 | NPY4R (0.47) | F10F2F11 | |
| SCHEMBL5848285 | 0.74 | HDAC3 (0.38) | HDAC3HDAC1ALDH1A1F10PLA2G4A | |
| SCHEMBL8808549 | 0.73 | HDAC3 (0.49) | HDAC3HDAC1ALDH1A1PLA2G4AHSPA9 | |
| SCHEMBL8800998 | 0.72 | HDAC3 (0.54) | HDAC3HDAC1 | |
| SCHEMBL23862150 | 0.72 | F11 (0.40) | ALDH1A1F10F2CTSKF11 | |
| SCHEMBL8801010 | 0.72 | F10 (0.44) | F10PRSS1F2CTSKF11 | |
| SCHEMBL29187204 | 0.72 | FDPS (0.39) | ALDH1A1CTSKHSPA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019483-A1 | LOW MOLECULAR WEIGHT BICYCLIC THROMBIN INHIBITORS | BIOCHEM PHARMA INC. (CA) | 1996-06-27 | — | — | WO | disclosed |