Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408082 | 0.90 | — | — | |
| SCHEMBL7409325 | 0.90 | — | — | |
| SCHEMBL7410695 | 0.88 | L3MBTL1 (0.45) | L3MBTL1 | |
| SCHEMBL7406898 | 0.88 | L3MBTL1 (0.45) | L3MBTL1 | |
| SCHEMBL7411267 | 0.85 | L3MBTL1 (0.48) | L3MBTL1 | |
| SCHEMBL7407549 | 0.84 | GPR119 (0.44) | L3MBTL1 | |
| SCHEMBL7412072 | 0.84 | L3MBTL1 (0.41) | L3MBTL1 | |
| SCHEMBL7402247 | 0.84 | L3MBTL1 (0.46) | L3MBTL1NPC1RAB9A | |
| SCHEMBL7413206 | 0.83 | UCHL1 (0.40) | — | |
| SCHEMBL7408913 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973775-A1 | PYROLOPYRROLONE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998043975-A1 | PYROLOPYRROLONE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-10-08 | — | — | WO | disclosed |