SCHEMBL741065

SCHEMBL741065

CCC([C]=O)C1CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.50
EPHX1 P07099 3/20 0.35
TP53 P04637 2/20 0.32
CYP2D6 P10635 2/20 0.31
LMNA P02545 2/20 0.31
ALDH1A1 P00352 2/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.31
MLNR O43193 1/20 0.31
ABCB11 O95342 1/20 0.31
EGFR P00533 1/20 0.31
FYN P06241 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
HTR1A P08908 1/20 0.31
CHRM5 P08912 1/20 0.31
ADRA2A P08913 1/20 0.31
ADORA3 P0DMS8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12987447 1.00 SHBG (0.50) SHBGEPHX1TP53CYP2D6LMNA
SCHEMBL3036277 0.98 SHBG (0.46) SHBGEPHX1
SCHEMBL9416078 0.93
SCHEMBL9415959 0.88
SCHEMBL1335896 0.83 SHBG (0.41) SHBGEPHX1TP53ALDH1A1CYP1A2
SCHEMBL6988843 0.79 SHBG (0.39) SHBGEPHX1CYP1A2TSHRSIGMAR1
SCHEMBL7458138 0.78 SHBG (0.38) SHBGEPHX1CYP1A2TSHR
SCHEMBL6590036 0.77 SHBG (0.50) SHBGEPHX1TP53LMNAKDM4E
SCHEMBL27526699 0.77 SHBG (0.50) SHBGEPHX1TP53LMNAKDM4E
SCHEMBL19812674 0.77 EPHX1 (0.50) SHBGEPHX1TP53CYP2D6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1301829-A4 RADIATION SENSITIVE COMPOSITIONS CONTAINING IMAGE QUALITY AND PROFILE ENHANCEMENT ADDITIVES FUJIFILM ELECTRONIC MATERIALS (US) 2006-06-28 EP claimed
EP-1301829-A1 RADIATION SENSITIVE COMPOSITIONS CONTAINING IMAGE QUALITY AND PROFILE ENHANCEMENT ADDITIVES ARCH SPECIALTY CHEMICALS, INC. (US) 2003-04-16 EP claimed
US-6514664-B1 Radiation sensitive compositions containing image quality and profile enhancement additives ARCH SPECIALTY CHEMICALS, INC. 2003-02-04 US claimed
WO-2002008834-A1 RADIATION SENSITIVE COMPOSITIONS CONTAINING IMAGE QUALITY AND PROFILE ENHANCEMENT ADDITIVES ARCH SPECIALTY CHEMICALS, INC. (US) 2002-01-31 WO claimed
WO-2023085402-A1 PEPTIDE HAVING INHIBITORY ACTIVITY ON FORMATION OF LEUKOCYTE EXTRACELLULAR TRAPS 平橋 淳一 2023-05-19 WO disclosed
US-11566047-B2 Peptide or pharmaceutically acceptable salt thereof, or prodrug thereof TOKYO UNIVERSITY OF PHARMACY & LIFE SCIENCES (JP) 2023-01-31 US disclosed
US-20190177370-A1 PEPTIDE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, OR PRODRUG THEREOF TOKYO UNIVERSITY OF PHARMACY & LIFE SCIENCES (JP) 2019-06-13 US disclosed
US-20170073373-A1 POLYMYXIN DERIVATIVES AND THEIR USE IN COMBINATION THERAPY TOGETHER WITH DIFFERENT ANTIBIOTICS SPERO THERAPEUTICS, INC. 2017-03-16 US disclosed
US-8383617-B2 Treatment of protein aggregation diseases PAD PHARMA LIMITED (GB) 2013-02-26 US disclosed
US-8138342-B2 11β-hydroxysteroid dehydrogenase type 1 active spiro compounds High Point Pharmacueticals, LLC (US) 2012-03-20 US disclosed
US-7892737-B2 Compositions, kits and methods pertaining to stability modulation of PNA oligomer/nucleic acid complexes Life Technologies Corporation (US) 2011-02-22 US disclosed
US-7858349-B2 Anti-cancer compounds THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2010-12-28 US disclosed
US-6281221-B1 Substituted 1,3-dioxan-5-ylamino-hererocyclic compounds, processes for their preparation and their use as pest control compositions HOECHST SCERING AGREVO GMBH (DE) 2001-08-28 US disclosed
US-6265350-B1 CONTROLLING HARMFUL FUNGI, INSECTS, ACARINA, MOLLUSKS AND NEMATODES HOECHST SCHERING AGREVO GMBH (DE) 2001-07-24 US disclosed
US-6107299-A INSECTICIDES; MITICIDES HOECHST SCHERING AGREVO GMBH (DE) 2000-08-22 US disclosed
WO-1999059979-A1 SUBSTITUTED PYRIDINE AND PYRIMIDINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES AVENTIS CROPSCIENCE GMBH (DE) 1999-11-25 WO disclosed
WO-1999059978-A1 SUBSTITUTED NITROGEN HETEROCYCLES AND THEIR USE AS PESTICIDES AVENTIS CROPSCIENCE GMBH (DE) 1999-11-25 WO disclosed
US-5889012-A INSECTICIDE, ACARICIDES, FUNGICIDES HOECHST-SCHERING AGREVO GMBH (DE) 1999-03-30 US disclosed
US-5859009-A Substituted spiroalkylamino and alkoxy heterocycles, processes for their preparation, and their use as pesticides and fungicides HOECHST SCHERING AGREVO GMBH (DE) 1999-01-12 US disclosed
EP-0599265-A1 Antibacterial, antifungal compound and its production method Takeda Chemical Industries, Ltd. (JP) 1994-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190177370-A1 PEPTIDE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, OR PRODRUG THEREOF MYOF, MSTN, VIP SHBG 661/4885EPHX1 4726/4885TP53 1820/4885
US-20170073373-A1 POLYMYXIN DERIVATIVES AND THEIR USE IN COMBINATION THERAPY TOGETHER WITH DIFFERENT ANTIBIOTICS PNISR, MRPS18A, RRP15 SHBG 4229/4885EPHX1 4404/4885TP53 3079/4885
US-11566047-B2 Peptide or pharmaceutically acceptable salt thereof, or prodrug thereof MYOF, MSTN, VIP SHBG 661/4885EPHX1 4726/4885TP53 1820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.