Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410737 | 0.88 | EPHX1 (0.46) | EPHX1ELANEHTR2CHTR2BCYP2D6 | |
| SCHEMBL29010884 | 0.82 | MMP1 (0.44) | ELANEHTR2CHTR2BCYP2D6TSHR | |
| SCHEMBL29010885 | 0.82 | ALDH1A1 (0.44) | ELANEHTR2CHTR2BKDM4ETSHR | |
| SCHEMBL11349211 | 0.79 | EPHX1 (0.59) | EPHX1KDM4EAPOBEC3AAPOBEC3GMEN1 | |
| SCHEMBL4069956 | 0.78 | TSHR (0.63) | ELANEHTR2CHTR2BTSHRALDH1A1 | |
| SCHEMBL630517 | 0.78 | TSHR (0.63) | ELANEHTR2CHTR2BTSHRALDH1A1 | |
| SCHEMBL693351 | 0.78 | TSHR (0.63) | ELANEHTR2CHTR2BTSHRALDH1A1 | |
| SCHEMBL12869701 | 0.78 | ALDH1A1 (0.45) | ELANEHTR2CHTR2BKDM4ETSHR | |
| SCHEMBL8304059 | 0.77 | HTR2C (0.55) | HTR2CHTR2BKDM4EMEN1KMT2A | |
| SCHEMBL8304057 | 0.77 | HTR2C (0.55) | HTR2CHTR2BKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1012180-A2 | HEPATITIS C INHIBITOR PEPTIDE ANALOGUES | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2000-06-28 | — | — | EP | disclosed |
| EP-1003775-A2 | HEPATITIS C INHIBITOR PEPTIDES | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999007733-A2 | HEPATITIS C INHIBITOR PEPTIDES | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 1999-02-18 | — | — | WO | disclosed |
| WO-1999007734-A2 | HEPATITIS C INHIBITOR PEPTIDE ANALOGUES | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 1999-02-18 | — | — | WO | disclosed |