Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444355 | 0.87 | MAPT (0.55) | MAPTLMNAHTTSMN1; SMN2NPSR1 | |
| Hydrochloric Acid SCHEMBL7433736 | 0.86 | MAPT (0.54) | MAPTLMNAHTTSMN1; SMN2NPSR1 | |
| SCHEMBL9429649 | 0.79 | CCNE2 (0.42) | MAPTLMNAHTTSMN1; SMN2NPSR1 | |
| SCHEMBL7442033 | 0.77 | PKM (0.45) | MAPTLMNAHTTSMN1; SMN2NPSR1 | |
| SCHEMBL10889292 | 0.77 | MAPT (0.59) | MAPTLMNAHTTSMN1; SMN2NPSR1 | |
| SCHEMBL10893573 | 0.76 | CYP3A4 (0.45) | MAPTLMNASMN1; SMN2MAPK10GAA | |
| SCHEMBL10886665 | 0.73 | PKM (0.61) | MAPTLMNAHTTSMN1; SMN2NPSR1 | |
| SCHEMBL10886129 | 0.73 | CYP1A2 (0.45) | MAPTLMNAHTTSMN1; SMN2NPSR1 | |
| SCHEMBL10887865 | 0.72 | CYP1A2 (0.46) | MAPTLMNAHTTSMN1; SMN2NPSR1 | |
| SCHEMBL7410880 | 0.71 | PDGFRB (0.49) | MAPTLMNAHTTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002088096-A1 | COMPOUNDS INHIBITING CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, PREPARATION AND USES THEREOF | NEURO3D (FR) | 2002-11-07 | — | — | WO | claimed |
| WO-2002088096-A1 | COMPOUNDS INHIBITING CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, PREPARATION AND USES THEREOF | NEURO3D (FR) | 2002-11-07 | — | — | WO | disclosed |