Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 8/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | EIF2AK1 | Q9BQI3 | 2/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7433736 | 0.99 | MAPT (0.54) | MAPTNPSR1HTTLMNASMN1; SMN2 | |
| SCHEMBL7442033 | 0.89 | PKM (0.45) | MAPTNPSR1HTTLMNASMN1; SMN2 | |
| SCHEMBL7410841 | 0.87 | MAPT (0.43) | MAPTNPSR1HTTLMNASMN1; SMN2 | |
| SCHEMBL10886665 | 0.85 | PKM (0.61) | MAPTNPSR1HTTLMNASMN1; SMN2 | |
| SCHEMBL9429649 | 0.85 | CCNE2 (0.42) | MAPTNPSR1HTTLMNASMN1; SMN2 | |
| SCHEMBL10886129 | 0.85 | CYP1A2 (0.45) | MAPTNPSR1HTTLMNASMN1; SMN2 | |
| SCHEMBL7410880 | 0.83 | PDGFRB (0.49) | MAPTNPSR1HTTLMNASMN1; SMN2 | |
| SCHEMBL10887865 | 0.83 | CYP1A2 (0.46) | MAPTNPSR1HTTLMNASMN1; SMN2 | |
| SCHEMBL7439770 | 0.81 | MAPT (0.47) | MAPTNPSR1HTTLMNASMN1; SMN2 | |
| Girisopam SCHEMBL637118 | 0.81 | MAPK10 (0.62) | MAPTNPSR1HTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288863-A | Cyclization; reacting hydrazine with an acetonyl-, chloro-, dimethoxybenzophenone | EGIS GYOGYSZERGYAR RT. (HU) | 1994-02-22 | — | — | US | disclosed |
| US-4322346-A | 5H-2,3-Benzodiazepine derivatives | KOROSI JENO | 1982-03-30 | — | — | US | disclosed |